We administered orally hydroxyurea in 70 patients of Beta-thalassemia with dose of 15-20 mg/kg/day.They have been followed up for a period of 4 months - 3 years. The age of the patients ranged from 1.5-25 years...Conclusion: Hydroxyurea remains a good option for patients who have presented with anemia at more than 2years of age. Long term side effects need to be evaluated.The