A trial of a new oral drug to remove iron in iron overloaded patients is now recruiting patients. This trial will take place at
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
http://clinicaltrials.gov/ct2/show/NCT00712738?rcv_s=06%2F27%2F2008&count=1000Please refer to this study by its ClinicalTrials.gov identifier: NCT00712738
Contacts
Contact: Patient Recruitment and Public Liaison Office (800) 411-1222 prpl@mail.cc.nih.gov
Contact: TTY 1-866-411-1010
Based upon recently published data in a rodent model, the purpose of this study is to determine if nifedipine will increase iron excretion in the urine among humans with increased levels of iron. Volunteers will be given a single oral dose (20mg) of nifedipine. Iron level in collections of urine will be measured and compared before and after nifedipine to determine if there is an associated increase in urinary iron excretion.
This appears to be a preliminary trial to see if there is any affect in humans. The trial will consist of a one-time dose of nifedipine. Interested patients in the eastern US who meet the eligibility criteria should consider participating in this trial. The results of this trial will surely lead to further trials if they show an added excretion of iron after this dose.