About Vitamin A..

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Offline Zaini

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About Vitamin A..
« on: October 30, 2008, 05:32:25 PM »
Hello everyone,

I was searching for a multi vitamin for myself,as i am feeling very low now a days,and i wasn't taking any multi vitamin,only foilc acid and Vitamin E,in my search i came across Multibionta which is manufactured by Merck.It contains,

Vitamin A (Palmitate) 5500 I.U
Vitamin D (Cholecalciferol) 500 I.U
Vitamin B1 (Thiamine Mononitrate) 10 mg
Vitamin B2 (Riboflavin) 10 mg
Vitamin B6 (Pyridoxine Hydrochloride) 5 mg
Vitamin B12 (Cyanocobalamin) 8 mcg
Vitamin C (Ascorbic Acid) 100 mg
Folic Acid 200 mcg
Nicotinamide 30 mg
Calcium D-Pantothenate 20 mg
Vitamin E (dl-Alpha tocepheryl acetate) 10 mg

At first i though it's a good one,apart from synthetic vitamin E,But what clicked me was the quantity of Vitamin A in it,i wasn't sure if that much vitamin A was required on daily basis,so i looked it up on internet and found this,

 From http://www.wellnessletter.com/html/ds/dsVitaminA.php

Quote
Vitamin A


Claims, Benefits: Important for vision, maintains immunity

Bottom Line: Deficiency is rare in developed countries. Since it's fat-soluble, dangerous levels can build up if you take large doses over time. Supplements are especially risky for pregnant women.

Full Article, Wellness Letter, July 2002:

New Advice About vitamin A

Vitamin A is essential for good health—notably for eyes and skin, immune function, reproduction, and bone growth. That's why nonfat and low-fat milk, margarine, and many breakfast cereals are fortified with it. However, high doses of vitamin A taken over time can be dangerous, especially for pregnant women (the vitamin is fat-soluble and is stored in the body, so levels can build up). Now a Harvard study suggests that Levels of vitamin A once considered safe and healthful may weaken women's bones and increase the risk of fractures.

The study of 70,000 postmenopausal nurses found that those who consumed the most vitamin A (equal to at least 6,600 international units, or IUs) from foods and/or supplements over an 18-year period had nearly double the risk of fractures com-pared with those consuming the least. A Swedish study in 1998 had similar findings, though other studies have found no such increased risk. It's theorized that moderate to high levels of vitamin A reduce bone growth and interfere with the ability of vitamin D to help the body utilize calcium.

However, both the Harvard and Swedish studies found that only "preformed" vitamin A, also called retinol, was linked to bone loss and fractures. The body converts beta carotene and many other carotenoids in vegetables and fruits into vitamin A, as needed. The studies found no adverse effect from carotenoids.

Sorting through the numbers

The newly revised daily Recommended Dietary Allowance (RDA) for vitamin A is equal to 2,333 IU daily for women, and 3,000 IU for men. The labels on foods and supplements use an older set of daily requirements called the "Daily Values," which includes 5,000 IU for vitamin A. Multivitamins typically contain 100% of the Daily Value. Recently, the Institute of Medicine, which determines the RDAs, set 10,000 IU as the safe upper limit for A.

So the amount found to be risky in the Harvard study (6,600 IU) is nearly three times the RDA for women, and one-third more than the Daily Value. But it is far below the "upper limit." That's why this finding is surprising.

(Note: To add to the confusion, two different units of measure are used for vitamin A. We've used IU here because that's what the FDA uses for the Daily Values—and thus that's what you'll see on the labels of foods and supplements. However, researchers express vitamin A activity in micrograms [a millionth of a gram]. The Institute of Medicine also uses micrograms for the RDA. If you want to convert IUs to micrograms, click here.)

Where it comes from

• Liver, which stores the vitamin, is very rich in it: a whop-ping 30,000 IU in 3 ounces of beef liver, and 13,000 IU in the same amount of chicken liver.

• Fish oil, from fish livers, is the most concentrated source of A (though the flesh of most fish has only modest amounts of the vitamin).

• Fortified breakfast cereals, including most instant oatmeal, have a fair amount—usually 500 to 1,000 IU (10 to 20% of the Daily Value) per serving.

• Whole milk has 300 IU per cup; nonfat and low-fat milk (which are fortified with A), 500 IU; butter or margarine, 400 to 500 IU per tablespoon; most hard cheese, about 250 IU per ounce.

• Most multivitamins contain 5,000 IU of vitamin A. But in some brands, 20 to 50% is in the form of beta carotene. Half the women in the Harvard study took multivitamins, which were the single largest source of A.

All you need to know

If you're a postmenopausal woman, keep track of your vitamin A intake:

• If you take a multivitamin, check the label. It should contain no more than 5,000 IU of vitamin A, and at least 20% of this should be in the form of beta carotene (the label will say, for instance, "50% as beta carotene" under vitamin A). There is no reason to stop taking your multi, which contains many nutrients important for healthy bones.

• Don't take separate vitamin A supplements. Even more important, women of childbearing age must not take them (doses as low as 10,000 IU a day increase the risk of birth defects). Men don't need them either.

• Don't worry about the vitamin A in milk or most other foods. It is hard to get high levels of vitamin A just from food, unless you eat liver or several servings of highly fortified cereal every day.

• Don't worry about carotenoids. These do not endanger your bones, since your body carefully regulates their conversion to vitamin A.

• Don't take cod liver oil.

• Don't go overboard and try to avoid vitamin A altogether. However, if you eat a variety of fruits and vegetables, which are rich in carotenoids, you don't need to worry about getting enough vitamin A.

 

Good news: Some makers of multivitamins have announced that they will soon lower the amount of preformed vitamin A in their pills and/or substitute more beta carotene for it. Similarly, in many margarines, some of the added vitamin A has already been replaced by beta carotene. Check the labels.


Now i am really confused should i stop taking this multivitamin,it's really hard to find a good multivitamin,choice is very limited in countries like mine,and most multivitamin contain iron,which i don't want to take.

Sharmin advised me to make a post about it as it can help all other members,so check your multi vitamins dears and tell me how much vitamin A they contain.

Andy? Any thoughts?

Zaini.
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Offline Sharmin

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Re: About Vitamin A..
« Reply #1 on: October 30, 2008, 05:59:46 PM »
Zaini,

I think that this information will be very useful to everyone if we can determine what a good dose of vitamin A is.  Most multivitamins seem to contain a fair bit of vitamin A - much more than the article which you present suggests.   Here is the post for the vitamin that I am taking and have suggested as a guide to others in finding multivitamins.  It contains 4000 IU of vitamin A.

http://www.thalassemiapatientsandfriends.com/index.php?topic=2164.0

Thanks for the great post Zaini,
Sharmin
Sharmin

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Offline Andy Battaglia

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Re: About Vitamin A..
« Reply #2 on: October 30, 2008, 06:12:45 PM »
I take 10,000 IU of vitamin A palmitate 3 times a week. I don't think that 5500 is out of line for a daily supplement. If there is a concern about too much A, take the multi 5-6 times per week.
Andy

All we are saying is give thals a chance.

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Offline Manal

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Re: About Vitamin A..
« Reply #3 on: October 30, 2008, 10:34:08 PM »
Hi Zaini

When i take mutivitamin i usually take the centrum which has 2500 IU and by the way it has no iron. But speaking of iron in multivitamins, usually it is in small amounts that you can not deprive your body of unless you have high readings of iron. It is not like taking iron pills alone as they are high in mg but in the mutivitamin they are low and there is always a possibility that you have iron deficiency if you totally avoid it.

manal

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Offline Zaini

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Re: About Vitamin A..
« Reply #4 on: October 31, 2008, 06:17:22 AM »
Hi Manal,

Although my hb readings are almost always low,but a couple years back when i tested my ferritin it was around 50,which is normal according to the refence range,so i didn't know that if taking iron was a good idea for me.

And about about vitamin A,i didn't know if vitamins can do any harm,i was just curious that if human body needs that much vitamin A on daily basis,that's why i searched about it.

Zaini.
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Offline Sharmin

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Re: About Vitamin A..
« Reply #5 on: October 31, 2008, 02:40:53 PM »
Zaini,

I think Andy's idea of taking the vitamin 5 or 6 days of the week is good - just in case that dose is too high. 

As for iron, there is more and more evidence that thal minors tend to absorb extra iron through the gut because they are anemic and there are more reports of iron stored in organs of thal minors as well. 

I agree with Manal that thals should not avoid iron all together, especially because women but maybe it would be a good idea to eat iron rich foods rather than having it in a supplement except in pregnancy or right after childbirth. 

Because thal minors break down there red blood cells more frequently than the average person (28 days) I suspect that more iron could be stored from that as well. 

Sharmin
Sharmin

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Offline Zaini

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Re: About Vitamin A..
« Reply #6 on: October 31, 2008, 06:02:22 PM »
Zaini,

I think Andy's idea of taking the vitamin 5 or 6 days of the week is good - just in case that dose is too high. 

As for iron, there is more and more evidence that thal minors tend to absorb extra iron through the gut because they are anemic and there are more reports of iron stored in organs of thal minors as well. 

I agree with Manal that thals should not avoid iron all together, especially because women but maybe it would be a good idea to eat iron rich foods rather than having it in a supplement except in pregnancy or right after childbirth. 

Because thal minors break down there red blood cells more frequently than the average person (28 days) I suspect that more iron could be stored from that as well. 

Sharmin

These exactly were the points in my mind,that's why i try to avoid iron in supplements,although i don't eat red meat much,or even green leafy vegetables,still my ferritin was in normal range.Do you think there would be any symptoms if we minors get iron overload,i know ofcourse it won't be that severe like majors,but still it's harm ful isn't it?

Zaini.
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Offline Manal

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Re: About Vitamin A..
« Reply #7 on: November 01, 2008, 12:06:04 AM »
One more thing Zaini, is that you have to do  a complete iron studies to evaluate iron levels. I say this because at certain times my ferritin was normal and my serum iron was severly below the normal range. At that time i started taking iron pills :thumbdown and after 3 months my Hb raised from 9 to 12.5   

manal

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Offline Zaini

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Re: About Vitamin A..
« Reply #8 on: November 01, 2008, 07:21:30 PM »
Good idea Manal, :hugfriend

I'll try to get my serum iron checked.

Zaini.
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Re: About Vitamin A..
« Reply #9 on: November 19, 2008, 02:15:50 PM »
good information. guys, is it true that aloe vera helps grow hair? can somebody share something about it? thanks

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Offline nice friend

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Re: About Vitamin A..
« Reply #10 on: November 19, 2008, 08:35:31 PM »
Hi mushroom-eater ,
 :welcome to the Family , i hope you will find this forum realy helping encouragin and caring.. i hope that  you will find here all the asnwer of ur concerns .. about aloe vera  , we have discussed much abt it here r i m quoting some link i hope u will find ur answers in these threads ..

http://www.thalassemiapatientsandfriends.com/index.php?topic=831.0

http://www.thalassemiapatientsandfriends.com/index.php?topic=329.0

http://www.thalassemiapatientsandfriends.com/index.php?topic=1088.0

http://www.thalassemiapatientsandfriends.com/index.php?topic=2267.0

Best Regards ..
Take care
Umair
Sometimes , God breaks our spirit to save our soul.
Sometimes , He breaks our heart to make us whole.
Sometimes , He sends us pain so we can be stronger.
Sometimes , He sends us failure so we can be humble.
Sometimes , He sends us illness so we can take better care of our selves.
Sometimes , He takes everything away from us so we can learn the value of everything we have.

===========
Umair

 

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