Chelation to start

Hi,

My son 9 years old having HbE-Beta Thalassemia.He is on regular transfusion from last one and half year ( transfusion gap is 5 week).
His weight is 23 Kg,current ferritine  is 850.
we have planned to start Asunra 600mg, please need your advice / comments on this.

regards

Dip

Dip,
Based on our experience, I will suggest to start on a very low dose initially (e.g. 10mg/kg weight or so) and then gradually increase the dose to the final dosage amount. Also try to give exjade with food to minimize stomach discomfort.

Dear Bostonian_04

Thank you for your suggestion . I am also having same opinion of starting with lower dose.

Regards

I agree. I like to see patients start at 1/3 dose for two weeks before deciding to raise the dose. A slow introduction greatly reduces the early side effects. And make sure the child stays well hydrated.

Dear Andy,

Thanks!

I have one more query, slightly different that subject topic,
Due to my Profession I may have to stay Two Years in South Korea, Do you have any experience or information about the treatment center in South Korea (Seoul)

Regards,
Dip

Just adding my two cents.

Our daughter Little Miss A is 12 years old and 65lbs. She is taking 375mg of exjade everyday. Her ferritin is below 1000.

I think 600mg is a bit two high, how did you come up with 600mg dose. Did the doctor recommended it.

Dip,

I was given this link for S Korea treatment. https://www.snuh.org/english/ihc/ihc04/sub02/sub01/

Dear Andy

Thanks for you information.

Dear Canadian Family

the above dose is suggested by doctor.
But currently I am giving slightly leass than 400mg.