Hi Rozitka,
According to Novartis, for your ferritin level, you should be using about 1500 mg per day (25 x 57= 1425).
http://www.novartis.com.au/PI_PDF/dsf.pdfDosage:
The lowest effective dose should be used.
In most patients average daily doses of 20 to 60 mg/kg body weight are adequate. Patients with a serum ferritin level of less than 2000 microgram/L require about 25 mg/kg/day. Patients with a serum ferritin level between 2000 and 3000 microgram/L require about 35 mg/kg/day. Patients with higher serum ferritin levels may require up to 55 mg/kg/day. It is inadvisable to regularly exceed an average daily dose of 50 mg/kg/day except when very intensive chelation is needed in patients who are no longer growing. If ferritin values fall below 1000 microgram/L, the risk of Desferal toxicity increases. Therefore, it is important to monitor these patients particularly carefully and to consider lowering the total weekly dose.
Note that the doses recommended represent the average daily dose. Since most patients receive the drug on less than 7 days per week, the actual dose per infusion usually differs from the average daily dose (e.g. if an average daily dose of 40 mg/kg is required and the patient receives the drug on 5 days per week, each infusion should contain 56 mg/kg).
Your weekly dose of desferal should be around 10 grams total.
It is difficult to be completely accurate with a recommended dosage because the effect of desferal differs depending on how long you take it each session. The longer you take desferal at one time, the more effective it is even if the dose is the same, so 1.5 grams taken over 18 hours will chelate more iron than if the same amount is taken over 12 hours. Because you are also using Ferriprox, you can have chelation going on 24 hours a day. It's suggested to take Ferriprox during the day and desferal at night. This combination is very effective at lowering iron and especially heart iron.
And a belated happy birthday to you.
