From Iraq to Pune, that’s one cell call!
Toddler suffering from thalessemia is the first patient to be treated in Pune with unrelated allogeneic stem cell transplant
DIPTI BARVE
Iraqi toddler Almaki Ridhadil was not in Pune for a fun visit. His parents had brought him to the city for thalessemia treatment. Hoping to find a bone marrow donor, they ended up going for unrelated allogeneic stem cell transplant and are now happy with the way their twoyear-old son is progressing.
Dr Vijay Ramanan, bone marrow transplant specialist at Ruby Hall Clinic, performed the procedure on Almaki for the first time in Pune.
In case of a thalessemia patient, a bone marrow transplant is considered to be the best mode of treatment. But in case of the toddler, this option did not work.
Ramanan said, “When Almaki and his parents came to our hopital, we tested bone marrow stem cells of his parents and those of his sister and two brothers. But they did not match. Then we thought of getting an unrelated allogeneic cord blood stem cell donor. We got one from the cord blood bank which matched with Almaki’s stem cells. We performed this procedure a month back and after this first phase of transplant, the patient has shown great improvment. The white blood cell count has increased in his body. We are looking forward to more improvement in his health.”
Ramanan added, “It is usually believed that autologous cord blood stem cell transplants (using the patient’s own stem cells) are useful for thales-semia patients. But unrelated allogeneic stem cell donors are the best option for those who have not preserved their cord blood stem cells.”
Ramanan also stressed on the need for allogeneic stem cell donors and cord blood stem cell donors in India, to help thalassemia patients.
Almaki’s mother Zainab said, “It was a great moment for me when we finally got the correct treatment for my younger son. We came to Pune with the hope that we will get the best treatment and now I am feeling relieved to see my son’t health improving so fast.”
ABOUT ALLOGENEIC STEM CELL TRANSPLANTS:
Allogeneic stem cell transplants refer to stem cells that are taken from one person and given to another. With these transplants, the donor’s cells must match the recipient’s tissue type (much like a blood transfusion needing to match the blood type of the person receiving it).
In many cases, the stem cell donor is related to the recipient, typically a brother or sister. However, stem cells from unrelated donors can be used if the tissue types match. It may also be possible to use cells from banked cord blood.
Little Almaki relaxes at Ruby Hall Clinic with his mother Zainab
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