Be sure not to give the patient Lactaid or anything else within a half hour of using the Exjade - as Exjade is to be taken on a completely empty stomach. I usually give Lil A the Lactaid a few hours before or after Exjade. For a while lil A was feeling bloated and he had lost his appetite. He lost 4lb as a result of this. Recently Little A has begun taking Exjade at night - I also use Lactaid when he has stomach issues - and thankfully his appetite has returned to normal and he has regained the weight he had lost. I hope it helps everyone:)Sharmin