Medical conditions that are associated with higher risk for flu complications include:AsthmaBlood disorders (such as sickle cell disease)Chronic lung disease (such as cystic fibrosis)Heart disease (such as congenital heart disease and congestive heart failure)Endocrine disorders (such as diabetes mellitus)Kidney disorders Liver disorders Metabolic disorders (such as inherited metabolic disorders and mitochondrial disorders)Weakened immune system due to disease or medication (such as people with HIV or AIDS, cancer, or those on chronic steroids)Receiving long-term aspirin therapy for chronic disorders Pregnancy