New Member, please help me.

Dip,

I would ask for a complete iron panel to be done before taking iron. Ferritin levels are deceiving in many cases and especially in intermedia. Unless iron deficiency is absolutely proved, you should not give iron.

Hello Manal
My sons Platelets readings are as follows
308 on 31st Jan (5 weeks after 1st transfusion)
548 on 25th Feb
543 on 29th March
360 on 9th April
586 on 20th May
605 on 1st July

Hello Andy,
Thanks for your advice.
Next time I am planning to go for CBC in some different Lab.

As per last CBC his Hb is 9.1 and RBC count is 4.6,so after getting next readinf I will think for complete iron panel.
Dip

Hi Dip,
  , have a nice time ....  best of luck ....

Best Regards
Take Care
Umair

Hi Dip

Though the platlets are above normal, my doctor once told me not to worry unless it passed one million. I still recommend doing the CBC in another lab and you can point out to the technician about having thal so he is more precise in differniating between platlets and fragmented red blood cells.


I am really happy to know about the HB, keep it up

Please consider too giving your son natureal vitamin E because it is a blood thinner in addition to its benefits as being an antioxidant

Take care, you are doing an excellent job

manal

Hello Manal,
Thank you for your advice.
I will let you know about the updated report soon.

dip

Hello manal  H,ello Andy
today I got the new CBC report of my son.
Hb come down from 9.1 to 8.3
RBC come down from 4.6 to 4.17.
MCV=64
MCH=19.9
MCHC=31.1
RDW=32.2
TLC=16
Platelets=396 earlier it was 605 and I was concern about this. This time I inform the Lab that the chidh is habing E-Beta thalassemia, so platelest count should be do keeping this things on mind.
 
according to this can anyone suggest me that I should go for giving oral iron or not, infact I am going to meet my doctor tomorrow, but erlier he suggested to give my son oral iron but I haven't do this, as thal should not take oral iron .
I dont know I am little bit confused today.
should I give oral iron?
should I increase Hydrea quantity???
(currently I am giving 12.5mg)

You really should have iron studies done before continuing to supplement with iron. Iron is almost never right for thal intermedias and majors.

hello dip and sorry for my late reply

I agree with Andy about having full iron studies before deciding anything that has to do with taking oral iron.

I still don't understand why the doctor suggested giving iron in the first place??

I am happy to know the the result of the platlets too, please keep us informed

take care
manal

Dear all
today I got the latest bloold test report of my son.

Ferritin=63.4
urea=30.6
creatinine=0.31
bilirubin(total)=2.89
bilirubine (indirect)=2.3
GGTP=7.8
SGPT=10.5
SGOT=39.9

CBC
HB=8.0 (before 45 days it was 8.3)
TLC=11.17
RBC=4.06(earlier it was 4.17)
platelets=376
PCV=25.7

I am giving my son 250mg hydrea (hydroxy-carbamide)
Is hydrea and hydroxyurea is same.
our doctor suggest me to give him 330mg hydroxyurea(cytodrox by Cipla)

please suggest

Yes, hydroxyurea is often referred to as hydrea. The platelets are back down to normal. It seldom is a problem when they are shown to be high. More often than not, it is the expertise of the lab techs that is in question. The stable Hb is a good sign. With his high HbF level, hydroxyurea has good potential to help keep his hemoglobin level from dropping.

Dear All,
Today I got the new CBC report for my son.
Currently his Hb is 7.9 g/dl before 2 month it was 8.0g/dl.
His Hb trends is as follows after 1st transfusion on 25th Dec 2009.

9.5 g/dl  on 31st Jan 2010
8.3 g/dl  on 25th Feb 2010
7.8 g/dl  on 28th Mar 2010
8.9  g/dl  on 09th Apr 2010
8.5 g/dl  on 20th May 2010
9.1 g/dl  on 1st Jul 2010
8.3 g/dl  on 15th Aug 2010
8.0 g/dl  on 29th Sep 2010
7.9 g/dl  on 26th Non 2010

From the above pattern can we say the haemoglobin is stable or it is continuously reducing/decreasing?
 Or he may need another transfusion in near future.
I dont know why it is decreasing, he had some loose motion and cough/cold before 4 week back.
Although I am going to meet my doctor tomorrow.

(He is taking 250 mg Hydrea since Feb 2010.)

Hi Dip,

Illness often does cause a drop in hemoglobin level, so this may explain the drop. Hb levels do vary a bit and are affected by the season and also by hydration. A well hydrated person might actually show a lower Hb even though there is no problem, so small changes should be expected from test to test. A physical observation of the child has to be included in any analysis of how well the drug is working. If growth is normal, activity level and appetite are good, these factors have to be taken into account as positives when hydroxyurea is involved.

If possible, L-carntine and magnesium should be taken with hydroxyurea to help maximize its affect.

It can't be predicted if he will need a transfusion in the future, but as long as the Hb doesn't drop below 7-8, depending on the observed health of the child, transfusions should not be needed.

Hello Andy,
Thanks for your reply.
should I consider the  natural resource ( food /vgetable  etc...) for L-carntine and magnesium or we should give him any form of  medicine.
Regarding the physical growth ,my son is 4 yrs 5 months old, his weight is 14.7 kg and height is 105cm.
He is under weight.
He gained 2kg weight and 10cm height in 11 months.He is very active but some time I realised that he become very tiered while plying.
If any body can share there experience abount the growth it will be very muh helpful to me.

Thank you
Dip

I think that because of the amounts needed, that you will need to give supplements and not just rely on diet. You can use natural derived supplements.

Hello Dip,

As a child I had similiar Hb levels. I was always the smaller and weaker child at my age in school. I had a small appetite and was very picky about what I ate. My favorite meal was breakfast and I ate lunch, but dinner was usually forced by my parents. Nothing really changed until the ages of 17 and 18yrs old. I grew to be very tall, but still thin. But i was more active in sports which may have help start the growth spurt.