New Member, please help me.

Dear All,
Today I got the new update of my son's blood report.

Hb=8.2
RBC=3.93
TLC=13.6
platelets=340

Urea=37,(earlier it was 30.6 on 30th sep 2010)
Creatinine=0.19 (earlier it was 0.31 on 30th sep 2010)

Bilirubin, total= 1.98
Bilirunin,Direct= 0.34
Bilirubin indirect=1.64

I am giving Hydrea 250 mg,
can any body give some idea wheather the Hydrea is doing some side effect on kindeney?
because Creatinine falls down below the lower limit !!!!!!! 

The drop in creatinine is actually a good sign because hydroxyurea can raise creatinine levels. What units were used to measure the creatinine?

Hello Andy
the units for urea and creatinine measured in mg/dl.

blood urea value is 37 mg/dl for my son, where as max. limit is 38 as per the repor I have.
Is the high value of urea is also because of HYDREA?

tomorrow i am going to meet his doctor.

Both creatinine and BUN (blood urea nitrogen) rise when using hydroxyurea. It is essential that patients stay well hydrated to ensure proper kidney function.

Dear All,
My sons, new CBC report is as follows

Hb=7.9
RBC=4.01
TLC=12.2
platelets=415


Bilirubin, total= 3.2
Bilirunin,Direct= 0.6
Bilirubin indirect=2.6

compared to last test his Hb fall down from 8.2 to 7.9 and also Bilirubin increased from 1.98 to 3.2.
I have increased the hydrea dose.
Is it that affect?
is it possible that increased dose of hydrea may decrease the HB or increase bilirubin?
or any other suppliment/food may destroying more Hb and producibg more bilirubine??

any experience,please share.



Monday I am going to meet his doctor.



Dip.

Dear All,

Do hydrea is having any relation with eyes iching??

dip

Dear All,

I need some advice
From last three months my son's Hb are like
7.3 on 26 th Nov
7.7 on 3rd Dec,
and now 7.1 on 10th Dec, he is suffering from cough and cold from last  ane and half month, i used to gave him medicine and anitibiotics just three weeks back but still he is having cough and cold and TLC are aroud 1400 at present.

Should I go for trnsfusion?
if anybody having such experience please share.

Thanks and regards,
Dip

Hi Dip,

The change in Hb isn't much but the prolonged cold symptoms are a concern, but I have seen the same thing with my 21 year old son who has not got rid of a cold after 2 1/2 months and several doctor's visits. I don't know if transfusing might help shake the cold and each transfusion does pose some transfusion risk, so my tendency is to avoid transfusions if not already transfusing, unless the patient is obviously more sickly overall and noticeable less energetic than previously.

I would hope other members with some real life experience could offer some advice here.

Hello Andy,

Thanks for your reply.
Today I meet his doctor(hematologist), and he is also having same openion not to go for transfusion.We will check his Hb after another couple of week.

regards,
Dip

Hello Andy,

Today I got new CBC report for my son.
there is no much deifference w.r.t earlier CBC done befor 2 week.
HB 7.2
TLC 13300
Platelets 758 earlier it was 660 (2 weeks back)
so plateles increased .
I dont understand why his Hb is not coming to the base value which is 8 to 8.5
he is alright for last 2weeks. no cough & cold.
Do u have comments.
this platelets counts may be wrong???

Regards,
Dip

Hi Dip,

Platelet counts vary from test to test and are often incorrect, as the smaller pale red cells of thalassemia are sometimes mistaken for platelets. It is also too soon after the illness to judge whether or not the Hb will go back to the old level, as it does take some time for new red blood cells to be produced.

Hi  Andy,

Thanks for your reply.
I met his hemato last week, he told me to wait for another month and check his HB again as Hb changed from 7.1 to 7.2 so it is quiety stable. regarding platlets he is telling not to worry. Actually we have stoped giving HU for last six month, my sons HB was around 8 to 8.5 before detection of Thalassemia and after giving HU for one and half year there is no segnificant changes. so he wants to make sure whether it is giving any advantage or not.

from last last 2 week im giving my sons one tea, call TULSI tea in indian language. good for cough and cold.
It is Antioxident, will it harmfull??

Regards,
Dip

Hi Dip,

No, it is not harmful. In fact, thals should consume as many antioxidants as possible as they counter much of the negative effects of the breakdown of red blood cells and also help to counter the effects of iron in the cells.

Hi Andy,

Thanks for your prompt reply & suggestion.
I will update after next CBC .

Regards
Dip

Hi All,

Today I got my son's new CBC report, his Hb is consistently low during last couple of months and today it reaches upto 6.6
In general his hb remains at a range of 8-8.5 but I stop Hydrea from last 7 month after continueing it for one and half years just to see whether Hydrea is working or not (as per doctor's advice).

I think I should againg star Hydrea, .Any suggestion from you is appreciated.

regards,
Dip