Boston Children's and other Thal center of Excellene in US are enrolling patients for URTH (, Unrelated BMT with reduced intensity for Thal) . This is a 1st of a kind joint multi center study. We met with the Doctor who is leading the study at Children's. After talking to her, we felt, there is still too much risk and we should wait for the study to complete. We were also told sickle cell also has similar study on-going.