why ..........?

When blood breaks down (hemolysis), bilirubin is secreated as a result. Bilirubin is a yellow pigment and when it is secreated in large amounts ( this means that Hb is decreasing ) it changes the the fluids of the body (urine), skin and eyes to yellow

manal

Hi there

it has been some time since i was last around.  How r u manal and how is Ahmad doing?

Do thal carriers also have hemolysis?

The amount of hemolysis that takes place in thal minors will be related to their overall Hb levels. A low level means that not enough normal red blood cells are produced and the irregular red blood cells will be filtered out by the body. This is hemolysis.

Jade, miss you loads . Where have you been???

We are fine, thanks God

Ahmad is enjoying his holidays with my parents by the sea at the north and my husband and i are stuck in some home renovations and maintance which are taking so long. Wish i can join them, the weather in Cairo is unbeliveable

Hope all of you are more than great

xoxox manal

I always look pale if i'm tired or when i'm  on my feet for even half an hour. What does that mean? My eyes don't look yellow though.

The person most likely to suffer from osteoporosis has pale skin

The reason why I chose to include this subject is because of the affect it can have on the feet; not so much from a fracture standpoint as I am not even sure I have seen a foot fracture that I attributed to osteoporosis in all my years of practice but rather another ramification of the disease as it relates to foot pain.
Many older individuals will present to the office complaining of generalized foot pain, more often than not both feet are affected. The patient generally cannot pinpoint an area that hurts but rather a complaint of nondescript pain in both feet. Yes, sometimes they may suffer from multiple arthritic joints, but they usually can then point to areas of the feet that hurt.

When the complaint is of pain with vague symptoms many times it can be from osteoporosis. As the bones of the feet demineralize over time, they become weaker but are still expected to support the whole body. This weakness in the bones reduces the strength of the individual bones and it is manifested as generalized foot pain.

for complete article : http://www.foot-pain-explained.com/osteoporosis.html

i hope its helpful .. :S ..


Best Regards
Take Care
Umair

does the eye colur change to yellow for all the thals or is it preventable cos i have seen 2-3 thals in my centre they look absolutely normal and u cant identify that they are thals if any special care needs to be taken pls let me know

The yellow color is caused by bilirubin, which is the result of the break down of red blood cells. Vitamins D & E and magnesium may have some positive effect on this, and should be taken regardless, but there are various factors for why blood breaks down early and much of this can't be affected.

Hi andy how are u .?
My brother is looks normal ,low iron and boold is between 8 and 10 most of time but eyes is dark yellow
....we dont know why ....but we want to know why ...?
TOTAL BILIRUBIN         47
DIRECT BILIRUBIN      2
INDIRECT BILIRUBIN    45

FaReS

What are the units of these results??

manal

Yes, what are the units and is hepatitis ruled out?

UNITS = umol\L
No last result of hepatitis was a all positive

The conversion factor for umol\L to mg/dL for bilirubin is 17.1, so divide the umol\L by 17.1 to find the value in mg/dL. This results in .12 mg/dL direct bilirubin (this is within normal range) and 2.75 mg/dL total bilirubin (this is double normal range). The high bilirubin level is directly related to hemolysis, the breakdown of the transfused red blood cells. This is also why his eyes are yellow. Please be aware that this level poses no real danger, but it does make gallstones more likely. There are various factors for why the blood breaks down, but transfused blood does not last long, and this is a common problem for thals. In an ideal world, we would have genotype matched blood that was fresh and 100% guaranteed to be disease free. This would help red blood cells to survive longer after transfusion, but there would still be premature hemolysis, resulting in a higher output of bilirubin. But we're not living in that world, so we do have to contend with things that could be reduced or eliminated. High bilirubin is one of these things...but,

Some things worth trying are nigella, vitamin D, magnesium, B complex and vitamin E. These may have a positive effect in several ways, and will hopefully have some effect on the hemolysis, and also the health of the liver and gallbladder.