Recruiting patient for Thalgen Finally! Good News about Gene Therapy Trials

What a wonderful news!!!! Best of luck to Dr Sadelain and his team. We are all eagerly waiting for the next update .

Praying for a grand success.
Waiting seems harder now it seems so close doesn't  it?
Zahra

Praying for a grand success.
Waiting seems harder now it seems so close doesn't  it?
Zahra

Sure it does, Zahra.

-P.

I pray to god for well being of all the patient, who is undergoing this trial . I am sure the day is not far when this therapy will be accessible and affordable to all.
best of luck to all of us.

Hello Andy,
Any further updates from Dr. Sadelain on the first few patients selected?? I pray for success in their efforts.

Please see reply from Memorial Sloan Kettering Cancer Center.

Question
Understood that it is hard to estimate when stem cell therapy can be widely available. However, if you can provide an estimate time of the phase I results in 2013.

Reply
Submitted by Memorial Sloan-Kettering  |  Wednesday, December 19, 2012 - 11:38 AM.
According to Dr. Boulad, “Although we will be able to estimate the amount of gene in the reinfused stem cells of at least three patients, the time interval for the expression of the gene is not very well known. This information will potentially be available by the end of the 2013.” Thanks for your comment!


Hope it helps...

Please see reply from Memorial Sloan Kettering Cancer Center.

Question
Understood that it is hard to estimate when stem cell therapy can be widely available. However, if you can provide an estimate time of the phase I results in 2013.

Reply
Submitted by Memorial Sloan-Kettering  |  Wednesday, December 19, 2012 - 11:38 AM.
According to Dr. Boulad, “Although we will be able to estimate the amount of gene in the reinfused stem cells of at least three patients, the time interval for the expression of the gene is not very well known. This information will potentially be available by the end of the 2013.” Thanks for your comment!


Hope it helps...

So it will take 1 more year to know the results of those who had undergone trials? That's long. Wasn't 40 days an expected ETA?

-P.

Pratik,

Let us hope and pray for the success of the trials, time is irrelevant.

So does that mean that the genes would take around a year to express themselves? So a patient who would undergo gene therapy now would start producing own blood after a year?

They actually expect to see expression within 40 days, but it will take much longer observation to see if it continues to express over time and to measure the safety and efficiency of the chemo regimen used.

Hi, on clinical trials.gov it says they estimate the study will last 2 years. Patience required.
Zahra

Praying for good news soon.........

This is extremely preliminary, but word is that the first patient is doing fine so far. This does not imply anything other than the patient's health is good after the chemo and introduction of the gene. We will find out more soon.

Encouraging signs.

Thanks for the update.

The timing of the release of this video is encouraging - as of yet however we do not know anything for certain about the progress of the gene therapy trials:

http://www.youtube.com/watch?v=gPPKvouhLvE&feature=youtu.be