Leeching as a substitute for phlebotomy 
Phlebotomy is a therapeutic technique that is commonly used in 
haemochromatosis and polycythemia vera. In some cases, phlebotomy 
cannot be performed because of intolerance or technical problems. We 
present an example of successful phlebotomy in hereditary 
haemochromatosis with the use of leeches. A 61-year-old female with a 
homozygous HFE C282Y mutation had previously needed venesection every 
3 months to maintain a ferritin level below 100 ug/l. Because of 
severe vasovagal reactions during venesection, she switched to therapy 
with leeches. During a typical bloodsucking procedure of one hour's 
duration eight leeches increased their body weight from 3 to 35 g. 
After the leeches had dropped off, bleeding continued for several 
hours . The wound dressing weighed 440 g more after therapy than 
before. This added up to about 475 g loss of blood per session, and 
was comparable to a typical venesection. Five leeching procedures 
reduced the ferritin level from 1200 ug/l to the very low level of 17 
ug/l because of over enthusiasm. We thank Mrs. L. Schumacher for her 
idea and for the photographs and also Mrs. S. Tolusso for performing 
the leeching procedure. 
Michael Nagler 
Walter A. Wuillemin 
Division of Haematology and Central Haematology Laboratory, Luzerner 
Kantonsspital , Lucerne , Switzerland. 
E-mail: walter.weille...@ksl.ch 
http://tinyurl.com/3v9bulw