Epogen is OK but is it really necessary? Many thal minors experience a drop in Hb during pregnancy, but nothing is done unless it drops below 8. The experience related here from moms is that the most important thing is folic acid, and a very high dose of 5-10 mg daily. The most successful thal minor pregnancies follow this practice. Folic acid is needed to build red blood cells and is the most important need, surpassing the need for iron, which may or may not be needed.