Packed Cell

Lokkhi,

Phenobarbital may lower the effectiveness of Exjade, but that is not a reason to not take the drug. Monitoring ferritin will tell you if the Exjade dose is high enough. The other option your doctor mentioned is desferal, which requires injections and administration through a pump. Exjade is much easier to start children on.

Hello Andy,

I want to start low dose Asunra as you advised 100 mg daily.After complete 2 years taking phenobarbital next May 16 may be the dose will be low slowly as earlier Doctor discussed with us.

 

Phenobarbital may lower the effectiveness of Exjade, but that is not a reason to not take the drug.

What do you think taking both seizure will occur?Have you any idea or experience pls share..

Hi Andy,

According to the above information if daily HB drops .10 to .15 then after 5 weeks it will be drop 4.20 (suppose .12 drops daily). After trnasfusion if my babies HB arise 13 then after 5 weeks it will be 8.8.As its near about 9 so we are giving her transfusion.


Am I right Andy?

What do you think my babies report is really wrong ?

Andy I need your opinion about my above thinking...

No, this will not cause seizure. The only issue is that phenobarbital can lessen the effect of the Exjade. As far as the Hb drops, you will only know as time passes. Each patient is different. Once a good record of Hb tests is established, you will have a better idea of how often transfusions will be needed. The gap between transfusions can get shorter as children get older.

Thanks a lot Andy for your helpful reply and advice.

The gap between transfusions can get shorter as children get older.

That's mean when my baby will grow up she needs transfusion within short gap ?  Why Andy I can't understand 

I think she is now taking her transfusion at HB level 9 on 5 weeks but when will be grow up then will  be take on HB level 8/7 on 7/8 weeks.So Transfusion will reduce.Quantity may increase for body weight but why timing ?

As people grow, the gap between transfusions usually shortens. Most majors need blood about every 3 weeks. For thals who make some of their own hemoglobin, this ability seems to drop with age, and transfusions that were 4-5 weeks apart become closer together.

For thals who make some of their own hemoglobin, this ability seems to drop with age,

Its not acceptable Andy...

Hi Lokhi Maa,

You are getting anxious of thing which may or may not happen in future (after 5 or 10 years).Why to worry now?

We all are hoping that after 5 or 10 or 15 years there will be much more advancement in treatment as so many researches are in pipeline..

So be hopefuls

and

Manage Hb @ 10-11 gms% before blood transfusion now

Thanks HANUMANT 

Hallo Andy Sir
                       As I am less transfuse so I don't know about the bad effects of taking whole blood over pack cell earlier . I'm quite less knowledgeable before coming this forum. 
In my last 5 transfusion I take 600 ml whole  blood   ( 2 bags ) each time. In the time of transfusion Out of 10 bags 2 bags will cause some allergic reaction and swelling  on face, ears, throught ( you say this is for antibody reaction ).  Then the doctor was stop the transfusion and inject me avil  and then after minimising the reaction he started the rest transfusion. Before starting transfusion they generally inject lasic or decadron injection.
 
Is this a proper way to take whole blood  ?

Should I taken some medication or consult with doctor about this for taking those precious transfusion of taking whole blood  ?  last B.T. 5 months ago.

What is the harmful side effects of taking whole blood  ?

If at your bt center packed cell blood product is not available than you should go to Kolkata for blood transfusion.

Let me know if u want to do so, i will try to arrange it for you

Abyaya Jyoty,

Whole blood is not suitable for thalassemics. It should be red blood cells, only, as this will greatly minimize reactions to the blood.

Thank you very much Andy Sir

Dharmesh Ji  
                    I don't know it earlier as I am less transfuse.  But after knowing it I find that pack cell is available in my district town Hospital
 (but some time crysis occurs there ) For future transfusion I have to contact there.

Hallo Andy Sir
                        One asking.  Please reply  this .
 I have seen some parents carry blood bags packing with ice for some thal patients  from one hospital to another when crysis occurs in hospital of their locality .
  Is it right to carry blood bags for transfusion   ?
   Is it safe   ?
   Is some damage occurs for carrying blood bags  ?
 

It is safe to transport blood as long as it remains cold and protected during transport. For some patients, it is a routine to do so.

Sir
     It must maintain temperature or cold condition during transport.   What other precautions should be taken for transportation of blood  ?

The bags should be transported using a cooler. This will keep it cold and protect it from any damage during transport. The type of cooler used to keep lunches cold is often used.