Gene Transfer Therapy Stage 1 Clinical Trials at Sloan Kettering

Andy,

Thanks for the update.

MSKCC updated the website yesterday. The major change is "This study is ongoing, but not recruiting participants.". Study completion date remains as July 2016.

https://clinicaltrials.gov/ct2/show/NCT01639690

SK presented at the meeting this week. I understand that they said that their process appears to be working and that they think the lesser preparation regimen was sufficient.

Thanks for the update.

So relieved to hear that lesser preparation regimen is still on horizon.

Thanks Andy for sharing the updates

Thank you for sharing Andy.  As parents we champion the lower intensity to protect our children from the affects of the preparation. 

Wishing this group success,

Sharmin

Thanks Andy for the update! good to hear that progress was being made at SKCC.

Andy, was there any other information that was shared in the meeting. how well were the patients coping, hb raise, etc.

Andy,
Thanks for sharing the update. multiple options for Gene therapy will always be useful for the patients. Hoping for more good news in ASH conference in December.

Primary results delayed by another year. Now July 2017......

https://clinicaltrials.gov/ct2/show/NCT01639690

Andy had already briefed us the situation in Sloan Kettering and politics going on. Please make your own conclusion.

They may just want to study it for another year. My understanding is that the rise in Hb has been steadily going up, but at a slow pace. I'm sure they want to see that this continues, even if slow, before making any conclusions.

Fair enough.

Thanks Andy

Another year delay. Estimated completion time has no been extended till July 2018. The study started in 2012. Not sure if they are on right track.....

https://clinicaltrials.gov/ct2/show/NCT01639690

 

I spoke with Pat yesterday.  He is still in court fighting for these trials to resume. This is the best vector, but trials have been stalled.