To Can.Fam. I've started Jadenu 3 months ago and at the beginning, for the first weeks, I did split the dose because of some gastrointestinal problems. It worked without any problems. Besides, I have never heard that we should not do that. The point is we dont have to do it but if it works better for some reason there is no problem so go ahead...
Jadenu is efective about some 18 hours so with split the dosis one could be covered full 24/7