carrier and sickle cell parents can take a chance for pregnancy?

My son is 20 months and is beta+ thal and sickle cell .he has
 taken hydroxyurea and folic acid plus lots of vitamins last 8 months.
He is currently doing fine and much active.  his  hb which is 8 to 9 last one year consistently.

HBF was 35.7 % and HBA was at 17.3 % HB S 42.9 and HB A2 4.1 % and no any blood transfusion ever.

Me carrier and my wife sickle cell and my question is we can take a chance for 2nd baby?

There is the same possibility with every pregnancy. The only way to be sure and avoid having another affected child is by using PGD and IVF, a costly process that can take multiple attempts to succeed.

Thanks dear for help me. Please tell me in detail what is  PGD and IVF?

PGD is preimplantation genetic diagnosis. The embryos are checked for status, so a non-carrier embryo is implanted via IVF, in vitro fertilization.

Thanks Dear for reply me.
we take chance because 25% Chance for major thal 25% chance for normal and 50% for carrier so can we Plan?

You can't plan anything based on chance. I know many families with three thal majors. The mathematical chances mean nothing.

you said that we can not plan?

No, it's completely chance and can't be affected by anything you do. You could easily have another child with the same sickle cell beta thal.

I know a family both of they are carrier and they not take any child within 12 yrs.

Last year they take a chance and after 13 yrs fortunately they got a child who is carrier.

But couple like us which chances not successful...

It's all just chance.

 

My First child who is 4 yrs old have E Beta Thalassemiia and need monthly transfusion,She have also ADHD,mild Autism Symptom and Seizure disorder.

Though she have lot of disorders but she is so much active and intelligent and special memory  . She have not forgot anything if she saw that just one time.Her seizure completely under control and now fine.Last seizure happen on 2014.Last month her EEG report is normal.

Every development normal but speech still not improve.She pointing,follow every instructions,understand our every languages,operate computer,play computer game but her words are few.

Now I have started Fish oil for her speech problem.

Dear Andy you know my present physical condition and above I shared about my baby but still I am interested for my 2nd child...

What to say !!!!! 
 

This is by no means to scare you but what does your child's doctors say about the epilepsy and the thalassemia??? Do they think there is a connection. Because I have heard in the past that there is a form of thalassemia with epilepsy.....

Lokkhi,

I can't answer this. It's up to you to decide on your family size.

Andy I just want to say there are lot of problems and risks but we parents are expect next child..

Its natural..

My son is beta plus and sickle cell. he  is quite fine without transfusion in 20 months of age so I can Plan for  2nd Baby?