carrier and sickle cell parents can take a chance for pregnancy?

Mubeen, it's not possible to say the outcome wouldn't be worse, but it is likely it wouldn't be. A child could be just a carrier of either or carry neither, in addition to having the same condition as your child does now.

They become wounds on their language, they are unable to eat food properly so his weight just 10 kg 

Me is carrier and my wife is sickle cell we are different category of thal our 2nd child can be a major thal? or same as 1st child beta+sickle cell?

It can't be beta major. It can be the same, beta+ sickle cell or lesser, carrier of one or neither..

Thanks Andy.
Please Tell me can be a normal? chance is possible?

Sickle cell and carrier both different category? child can be with major thal and beta+sickle cell and normal?

sickle cell and beta plus patients can Iron over load? Is it possible?

If transfusions are required, iron overload can occur. If the Hb is chronically low, less than 9-9.5, iron loading can take place over time.

Mubeen,
There are 3 possibilities for children you might have.
1) HbE sickle cell.  25% chance.
2) Carrier of HbE, or sickle cell, but not both. 50% chance.
3) Non-carrier of either. 25% chance.

Thanks dear for reply me

Can we give iron containing diet in this case? Like mango , liver. Dates

Dear me and my partner carrier and sickle cell . but HbE sickle cell and 
 Carrier of HbE what is this? please describe me in detail 

Mubeen, do not avoid veg foods that contain iron. There are too many other nutrients in these foods that are needed, and veg iron is not highly absorbed.

One of you carries HbE. One of you carries sickle cell. That is why your child has HbE sickle cell. Both affect the beta globin gene.

Again thanks dear