A high MPV is a common feature of thal minor. High B12 is not, but is actually beneficial for thal minors. During pregnancy, many thal minors take as high as 5 mg folate daily. This helps to keep the Hb up. Also, if you are not already taking it, add natural vitamin E to your regimen, as it helps to combat the clotting issues often found in thal minor, which can lead to miscarriage.