Hi Everyone,

Hopefully this post finds you all healthy. I am happy to be back after quite a while, writing this post on this incredible platform.

I am a 24-year-old thalassemia major patient from India weighing 65kgs, taking chelation therapy of desirox 2500mg per day every 2 consecutive days & kelfer 4000mg every 3rd day after 2 consecutive days of desirox. (Eg:- Mon&Tues – Desirox, Wed- Kelfer & so on). Please note that my liver has a severe iron overload, my pancreas has a moderate iron overload & no iron overload in heart.

My Recent Liver Function test (LFT) report showed bilirubin-total(B/T) of 5.0, bilirubin-indirect(B/ID) of 4.14 & bilirubin-direct(B/D) of 0.86 which is way much higher than the normal limits. I also noticed a steady rise in levels of B/T, B/ID and B/D compared to a year ago. Please note that my SGPT level is 42 and SGOT level is 45. Due to high B/T, I notice dark urine many times in a day and somewhat yellowish skin.

Is this increase in the above levels due to Desirox dosage? Can it be Gilbert Syndrome (which I haven’t tested yet)? Can it be controlled by any home remedies?  Is it harmful to the liver and body in the long run? One of my doctors said that increased B/T readings can lead to Jaundice more often!!

Request Andy for expert advice.

Report attached below.

Regards,
Sagar.

Hi Andy,

Thank you for your response. As per the CBC blood work, my 11 year old son's hemoglobin is as follows :

     Hemoglobin       10.8       (11.7-14.1).

Hemoglobin Electrophoresis shows "Consistent with Thal Minor".

Do you recommend any other testing ? We are hoping for him to grow more and gain some weight.

Thanks!

Sir please suggest me, should i go for a haploidentical BMT for my single 5 years thalassemia GIRL at Appolo Hospital Delhi.

Age - 5 years
weight - 18 kgs
Ferritin  - 2200 (as on 22/10/22)

IP6 is a very mild supplement. I would suggest one capsule for a child, but more would not harm the child. It can be opened and mixed into food if swallowing a capsule is an issue.

Thank you so much Andy! I just ordered B12 and Magnissuim vitamins.