Hello! I was wondering if any of you Thal. majors get back pains prior to your transfusions. For the last 3 years, I've been getting really bad back pains about a week before my transfusion. The only thing that makes me feel better is to stand up and walk around - even if the pain comes in the middle of the night. Needless to say, I've had many sleepless nights. No medicine has seemed to help relieve the back pain. I just have to suffer through it until it passes. I'm open for suggestions on preventing or relieving the pain. Thanks for your help!